4 May 2018

Chris de Zeeuw

Neuroscience Symposium
De Zeeuw Group

The Neuroscience Symposia are organized weekly by the Netherlands Institute for Neuroscience. The presentations are given by researchers from the institute or by guest speakers. The title and content of the symposium is usually made known in the week prior to the presentation.

Colloquium room – Netherlands Institute for Neuroscience

4:00 pm – Neural circuits for cognitive control of timing
4:45 pm – Discussion and drinks

Musicians can perform at different tempos, speakers can control the cadence of their speech, and humans can flexibly vary their temporal expectation of events. In the first part of the talk, I will outline a neural mechanism that we have identified for such deliberate control of timing. We record from the medial frontal cortex of monkeys trained to perform flexible timing tasks and discover a temporal code that enables such behavior. While these functions represent deliberate control of timing, humans also exhibit flexibility while estimating time intervals, which is realized by optimizing information from prior knowledge and noisy measurements. Bayesian decision theory provides a normative framework to understand such behavior. In the second part of the talk, I will propose a mechanism for how Bayesian timing could be implemented in cerebellar circuits.