15 November 2019

Dr. Zhenyu Gao

Neuroscience Symposium
Lohmann Group

The Neuroscience Symposia are organized weekly by the Netherlands Institute for Neuroscience. The presentations are given by researchers from the institute or by guest speakers. The title and content of the symposium is usually made known in the week prior to the presentation.

Colloquium room – Netherlands Institute for Neuroscience

4:00 pm – The new aspects of Cerebro-cerebellar circuits and sensorimotor control
4:45 pm – Discussion and drinks

It is well accepted that cerebrum and cerebellum play their unique roles in sensorimotor integration and learning. While extensive theoretical and experimental studies are crystalizing the computational principles of the cerebral and cerebellar circuits, relative little is known about the signal processing between cerebrum and cerebellum. In principle, cerebral cortex provide information to cerebellum, via several intermediate subcortical nuclei, in the forms of mossy and climbing fiber inputs. In return, cerebellar nuclei neurons innervate vast number of midbrain regions that relay information to different regions of cerebral cortex. Our recent research focuses on understanding the relevant cerebro-cerebellar circuits and their computational principles in specific sensorimotor tasks. Drawing from experiments using anatomical, behavioral, pharmacological, optogenetic and electrophysiological tools, I will discuss our recent efforts in dissecting the anatomical and functional organization of the cerebro-cerebellar circuits in the context of motor preparation and execution.