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James E. McCutcheon


The Neuroscience Symposia are organized weekly by the Netherlands Institute for Neuroscience. The presentations are given by researchers from the institute or by guest speakers. The title and content of the symposium is usually made known in the week prior to the presentation.

The symposium takes place online. A link will be provided via e-mail.

Guest speaker Susanne la Fleur

4:00 pm – Investigating the neural and behavioral basis of protein appetite

Abstract
Intake of dietary protein is tightly controlled in many species, however, the neural structures that allow such control are not well defined. We have shown that when rats and mice are kpt on a diet that is low in protein their macronutrient preference changes such that they consume more protein, relative to carbohydrate. In addition, protein-restricted rats show greater motivation for protein-rich food when required to lever press than do rats on a control diet. Finally, using fiber photometry we have shown that this protein appetite is associated with greater neural activation of the ventral tegmental area when rats are consuming protein vs carbohydrate.