Joris de WitNeuroscience Symposium
The Neuroscience Symposia are organized weekly by the Netherlands Institute for Neuroscience. The presentations are given by researchers from the institute or by guest speakers. The title and content of the symposium is usually made known in the week prior to the presentation.
Guest speaker Joost Verhaagen
Colloquium room – Netherlands Institute for Neuroscience
4:00 pm – Patterning the synaptic network
4:45 pm – Discussion and drinks
The nervous system consists of billions of neurons that are precisely connected through synapses. Unraveling how neurons form appropriate synaptic connections during development is a key challenge in neuroscience and is essential to understand brain function and disease. Neural circuit formation critically relies on cell-cell recognition and communication mediated by cell-surface ligands and receptors. The complexity of the cell-surface interactions that pattern precise synaptic connectivity is only beginning to emerge. In this seminar, I will focus on synaptic adhesion molecules and discuss novel findings on the role of these proteins in specifying connectivity, structure and function of the synaptic network.