14 September 2018

Scott Kanoski

Neuroscience Symposium
La Fleur Group

The Neuroscience Symposia are organized weekly by the Netherlands Institute for Neuroscience. The presentations are given by researchers from the institute or by guest speakers. The title and content of the symposium is usually made known in the week prior to the presentation.

Colloquium room – Netherlands Institute for Neuroscience

Guest speaker Susanne La Fleur

4:00 pm – Control of feeding and food impulsivity by novel neuropeptide signaling pathways

Melanin-concentrating hormone (MCH), a neuropeptide produced primarily in the lateral hypothalamus and zona incerta, potently increases food intake and is a clinically-relevant target system for obesity treatment. However, the behavioral and neuronal mechanisms mediating MCH effects on food intake are largely unknown. Our findings using rodent models reveal that MCH neurons promote different aspects of feeding behavior, including habitual feeding, reward-based excessive feeding, and impulsive responding for palatable food. Data will be presented supporting a model whereby MCH control of different aspects of feeding behavior occurs through distinct downstream neural signaling pathways.

4:45 pm – Discussion and drinks