Swammerdam Lecture with Elizabeth Buffalo


Host: Shanice Beerepoot, MD MSc. & Koen Seignette, MSc.

The symposium will be held in a hybrid form. You are welcome in the Colloquium room or online via Zoom.

Tuesday October 11th 2022 at 16:00: Neural dynamics of memory formation in the primate hippocampus

The in-person meeting is followed by a reception.

Our understanding of the hippocampus has been framed by two landmark discoveries: the discovery by Scoville and Millner that hippocampal damage causes profound and persistent amnesia and the discovery by O’Keefe and Dostrovsky of hippocampal place cells in rodents. However, it has been unclear to what extent spatial representations are present in the primate brain and how to reconcile these representations with the known mnemonic function of this region. Elizabeth will discuss a series of experiments that have examined neural activity in the hippocampus and adjacent entorhinal cortex in monkeys performing behavioral tasks including spatial memory tasks in a virtual environment. These data demonstrate that behavioral task structure has a significant influence on hippocampal activity, with neurons responding to all salient events within the task. Taken together, these data are consistent with the idea that activity in the hippocampus tracks ongoing experience in support of memory formation.



A masterclass will be organised for interested PhD students that will take place at the Netherlands Institute for Neuroscience (in person) right before the lecture 14:00-16:00h. The masterclass will be an informal yet in-depth discussion on your research, with input from Elizabeth as well as other attending PhD candidates. The exact format will depend on the number of interested PhD candidates, but will consist of short talks by candidates on their PhD work followed by a general discussion on the data and related topics.

See ONWAR website for more information