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Sustained high expression of human FVII following AAV8-mediated gene delivery in mice

Research group Verhaagen Group
Publication year 2025
Published in Molecular therapy. Methods & clinical development
Authors Andrea D'Amico, Bas Blits, Joëlle van den Herik, Fred de Winter, Paul H P Kaijen, Barbara Hobo, Alexander Henrik van Asbeck, Joost Verhaagen, David G M Mosmuller, Jan Voorberg
More information about: Sustained high expression of human FVII following AAV8-mediated gene delivery in mice View publication (PDF)

Activated alpha 9 integrin expression enables sensory pathway reconstruction after spinal cord injury

Research group Verhaagen Group
Publication year 2025
Published in Acta neuropathologica communications
Authors Katerina Stepankova, Barbora Smejkalova, Lucia Machova Urdzikova, Katerina Haveliková, Fred de Winter, Stepanka Suchankova, Joost Verhaagen, Vit Herynek, Rostislav Turecek, Jessica Kwok, James Fawcett, Pavla Jendelova
More information about: Activated alpha 9 integrin expression enables sensory pathway reconstruction after spinal cord injury View publication (PDF)

The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression

Research group Verhaagen Group
Publication year 2025
Published in Molecular Neurodegeneration
Authors Callan L Attwell, Inés Maldonado-Lasunción, Ruben Eggers, Bastiaan A Bijleveld, Ward M Ellenbroek, Natascha Siersema, Lotte Razenberg, Dédé Lamme, Nitish D Fagoe, Ronald E van Kesteren, August B Smit, Joost Verhaagen, Matthew R J Mason
More information about: The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression View publication (PDF)

A Study on Potential Sources of Perineuronal Net-Associated Sema3A in Cerebellar Nuclei Reveals Toxicity of Non-Invasive AAV-Mediated Cre Expression in the Central Nervous System

Research group Verhaagen Group
Publication year 2025
Published in International Journal of Molecular Sciences
Authors Geoffrey-Alexander Gimenez, Maurits Romijn, Joëlle van den Herik, Wouter Meijer, Ruben Eggers, Barbara Hobo, Chris I De Zeeuw, Cathrin B Canto, Joost Verhaagen, Daniela Carulli
More information about: A Study on Potential Sources of Perineuronal Net-Associated Sema3A in Cerebellar Nuclei Reveals Toxicity of Non-Invasive AAV-Mediated Cre Expression in the Central Nervous System View publication (PDF)

Hyperactive delta isoform of PI3Kinase enables long distance regeneration of adult rat corticospinal tract

Research group Verhaagen Group
Publication year 2025
Published in Molecular Therapy
Authors Karova Kristyna, Polcanova Zuzana, Knight Lydia, Suchankova Stepanka, Nieuwenhuis Bart, Holota Radovan, Herynek Vit, Machova Urdzikova Lucia, Turecek Rostislav, Kwok C Jessica, Joelle van den Herik, Joost Verhaagen, Eva Richard, Fawcett W James, Jendelova Pavla
More information about: Hyperactive delta isoform of PI3Kinase enables long distance regeneration of adult rat corticospinal tract View publication (PDF)

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