Publications

Daniela Carulli, Robin Broersen, Fred de Winter, Elizabeth M Muir, Maja Mešković, Matthijs de Waal, Sharon de Vries, Henk-Jan Boele, Cathrin B Canto, Chris I De Zeeuw, Joost Verhaagen Cerebellar plasticity and associative memories are controlled by perineuronal nets Proceedings of the National Academy of Sciences of the United States of America 117 (2020) 6855-6865 Download

Jelmer Willems, Arthur P H de Jong, Nicky Scheefhals, Eline Mertens, Lisa A E Catsburg, Rogier B Poorthuis, Fred de Winter, Joost Verhaagen, Frank J Meye, Harold D MacGillavry ORANGE PLoS Biology 18 (2020) e3000665 Download

Ruben Eggers, Fred de Winter, Lotte Smit, Maruelle Luimens, Elizabeth M Muir, Elizabeth J Bradbury, Martijn R Tannemaat, Joost Verhaagen Combining timed GDNF and ChABC gene therapy to promote long-distance regeneration following ventral root avulsion and repair FASEB Journal (2020) Download

Bart Nieuwenhuis, Barbara Haenzi, Sam Hilton, Alejandro Carnicer-Lombarte, Barbara Hobo, Joost Verhaagen, James W Fawcett Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract Gene Therapy (2020) Download

Maria João Godinho, Jonas L Staal, Vidya S Krishnan, Stuart I Hodgetts, Margaret A Pollett, Douglas P Goodman, Lip Teh, Joost Verhaagen, Giles W Plant, Alan R Harvey Regeneration of adult rat sensory and motor neuron axons through chimeric peroneal nerve grafts containing donor Schwann cells engineered to express different neurotrophic factors Experimental Neurology 330 (2020) 113355 Download

Ruben Eggers, Fred de Winter, Cleo Arkenaar, Martijn R Tannemaat, Joost Verhaagen Enhanced regeneration and reinnervation following timed GDNF gene therapy in a cervical ventral root avulsion Experimental Neurology 321 (2019) 113037 Download

Jeroen Melief, Marie Orre, Koen Bossers, Corbert G van Eden, Karianne G Schuurman, Matthew R J Mason, Joost Verhaagen, Jörg Hamann, Inge Huitinga Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis Acta neuropathologica communications 7 (2019) Download

R. Eggers, Fred De Winter, S.A. Hoyng, Rob C Hoeben, M.J. Malessy, M Tannemaat, J. Verhaagen Timed GDNF gene therapy using an immune-evasive gene switch promotes long distance axon regeneration. Brain 142 (2019) 295-311 Download

Elena Maria Boggio, Erich M Ehlert, Leonardo Lupori, Elizabeth B Moloney, Fred De Winter, Craig W Vander Kooi, Laura Baroncelli, Vasilis Mecollari, Bas Blits, James W Fawcett, Joost Verhaagen, Tommaso Pizzorusso Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex Molecular Neurobiology 56 (2019) 5987-5997 Download

E Muir, F De Winter, J Verhaagen, J Fawcett Recent advances in the therapeutic uses of chondroitinase ABC Experimental Neurology 321 (2019) 113032 Download

Yu-Ting Hu, Xin-Lu Chen, Shu-Han Huang, Qiong-Bin Zhu, Si-Yang Yu, Yi Shen, Arja Sluiter, Joost Verhaagen, Juan Zhao, Dick Swaab, Ai-Min Bao Early growth response-1 regulates acetylcholinesterase and its relation with the course of Alzheimer's disease Brain Pathology 29 (2019) 502-512 Download

Seçil Uyaniker, Sophie J F van der Spek, Niels R Reinders, Hui Xiong, Ka Wan Li, Koen Bossers, August B Smit, Joost Verhaagen, Helmut W Kessels The Effects of Sindbis Viral Vectors on Neuronal Function Frontiers in Cellular Neuroscience 13 (2019) 362 Download

James W Fawcett, Joost Verhaagen Intrinsic Determinants of Axon Regeneration Developmental Neurobiology 78 (2018) 890-897 Download

E.R. Burnside, Fred De Winter, Athanasios Didangelos, Nicholas D James, E.C. Andreica, H. Layard-Horsfall, E.M. Muir, J. Verhaagen, E.J. Bradbury Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury. Brain 141 (2018) 2362-2381 Download

J. Verhaagen, B. Hobo, Erich M E Ehlert, R. Eggers, Joanna A Korecka, Stefan A Hoyng, Callan L Attwell, Alan R Harvey, Matthew R J Mason Small Scale Production of Recombinant Adeno-Associated Viral Vectors for Gene Delivery to the Nervous System Methods in Molecular Biology 1715 (2018) 3-17 Download

Bart Nieuwenhuis, B. Haenzi, M.R. Andrews, J. Verhaagen, J.W. Fawcett Integrins promote axonal regeneration after injury of the nervous system Biological Reviews 93 (2018) 1339-1362 Download

Inés Maldonado-Lasunción, J. Verhaagen, Martin Oudega Mesenchymal Stem Cell-Macrophage Choreography Supporting Spinal Cord Repair Neurotherapeutics 15 (2018) 578-587 Download

Callan L Attwell, Mike van Zwieten, J. Verhaagen, M.R.J. Mason The dorsal column lesion model of spinal cord injury and its use in deciphering the neuron-intrinsic injury response Developmental Neurobiology 78 (2018) 926-951 Download

J A Korecka, E B Moloney, R Eggers, B Hobo, S Scheffer, N Ras-Verloop, R Jeroen Pasterkamp, D F Swaab, A B Smit, Ronald E van Kesteren, K Bossers, J Verhaagen Repulsive guidance molecule a (RGMa) induces neuropathological and behavioral changes that closely resemble Parkinson's disease The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (2017) 9361-9379 Download

E. Moloney, B. Hobo, Fred De Winter, J. Verhaagen Expression of a Mutant SEMA3A Protein with Diminished Signalling Capacity Does Not Alter ALS-Related Motor Decline, or Confer Changes in NMJ Plasticity after BotoxA-Induced Paralysis of Male Gastrocnemic Muscle PLoS One 12 (2017) e0170314 Download