Lohmann Group

Synapse and Network Development

The development of specific synaptic connections between nerve cells is a fundamental step during the maturation of the brain, but its underlying mechanisms are largely unknown. To investigate how neurons establish specific connections, we apply high resolution imaging and electrophysiology in brain slices and in vivo.

Our goal is to identify patterns of neuronal activity, forms of calcium signaling and molecular factors that regulate synapse development. We focus on the local regulation of synapse maturation and its relationship with activity patterns in the entire cell and the emerging network.



Lohmann Group

Mariska van Lier, M Hadi Saiepour, Koen Kole, Juliette Cheyne, Nawal Zabouri, Thomas Blok, Yi Qin, Emma Ruimschotel, J Alexander Heimel, Christian Lohmann, Christiaan N Levelt Disruption of critical period plasticity in a mouse model of Neurofibromatosis type 1 The Journal of neuroscience : the official journal of the Society for Neuroscience 40 (2020) 5495-5509 Download

All publications


No jobs available
View all vacancies