Swaab Group
Neuropsychiatric Disorders
The hypothalamus regulates and integrates a wide variety of endocrine, autonomic and behavioral processes which are essential for the organism’s survival and reproduction. The hypothesis that guides our research is that disturbances of the functional activity of the human hypothalamus may develop into neurological, psychiatric or (neuro)endocrine disorders.
The present research is focusing on two research objectives:
- To determine the hypothalamic basis of signs and symptoms of psychiatric, neurological and neuroendocrine disorders.
- To reactivate metabolically impaired neurons in Alzheimer patients in order to maintain or restore function.
The aim of both research lines is to find putative factors and targets for therapeutic strategies.
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Additional information and articles
- Research Theme 1
- Research Theme 2
- ‘A biological marker for people at risk for suicide. That would be wonderful’
Publications
Histamine-4 receptor antagonist ameliorates Parkinson-like pathology in the striatum Brain, Behavior, and Immunity 92 (2021) 127-138 Download
Our employees

Yangjian Qi
PhD student

Zala Slabe
PhD student

Nicole Breeuwsma
Technician

Jochem Stormmesand
Student

Lin Zhang

Michel Hofman
Senior Scientist

Ronald Verwer
Senior Scientist

Zhao Juan

Arja Sluiter
Technician

Dick Swaab
Department head

Bart Fisser
Technician

Rawien Balesar
Technician

Ai-min Bao
Visiting professor