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Meeting summary of The NYO3 5th NO-Age/AD meeting and the 1st Norway-UK joint meeting on ageing and dementia

Research group De Zeeuw
Publication year 2024
Published in The journals of gerontology. Series A, Biological sciences and medical sciences
Authors He-Ling Wang, Richard Siow, Tomas Schmauck-Medina, Jianying Zhang, Per Morten Sandset, Clare Filshie, Øystein Lund, Linda Partridge, Linda Hildegard Bergersen, Lene Juel Rasmussen, Konstantinos Palikaras, Ioannis Sotiropoulos, Jon Storm-Mathisen, David C Rubinsztein, Maria Grazia Spillantini, Chris I De Zeeuw, Leiv Otto Watne, Martin Vyhnalek, Katerina Veverova, Kristina Xiao Liang, Nektarios Tavernarakis, Vilhelm A Bohr, Koutaro Yokote, Janna Saarela, Hilde Nilsen, Efstathios S Gonos, Morten Scheibye-Knudsen, Guobing Chen, Hisaya Kato, Geir Selbæk, Tormod Fladby, Per Nilsson, Anne Simonsen, Dag Aarsland, Sofie Lautrup, Ole Petter Ottersen, Lynne S Cox, Evandro F Fang

Unhealthy ageing poses a global challenge with profound healthcare and socioeconomic implications. Slowing down the ageing process offers a promising approach to reduce the burden of a number of age-related diseases, such as dementia, promoting healthy longevity in the old population. In response to the challenge of the ageing population and with a view to the future, Norway and the UK are fostering collaborations, supported by a "Money Follows Cooperation agreement" between the two nations. The inaugural Norway-UK joint meeting on ageing and dementia gathered leading experts on ageing and dementia from the two nations to share their latest discoveries in related fields. Since ageing is an international challenge, and to foster collaborations, we also invited leading scholars from 11 additional countries to join this event. This report provides a summary of the conference, highlighting recent progress on molecular ageing mechanisms, genetic risk factors, DNA damage and repair, mitophagy, autophagy, as well as progress on a series of clinical trials (e.g., using NAD+ precursors). The meeting facilitated dialogue among policy makers, administrative leaders, researchers, and clinical experts, aiming to promote international research collaborations and to translate findings into clinical applications and interventions to advance healthy ageing.

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