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Stress-Axis Regulation by Vitamin D-3 in Multiple Sclerosis

Research group Huitinga
Publication year 2018
Published in Frontiers in Neurology
Authors I. Huitinga, Linda Rolf, Jan Damoiseaux, Dorien Kimenai, Jody van den Ouweland, Raymond Hupperts, Joost Smolders,
The order of authors may deviate from the original publication due to temporary technical issues.

Multiple sclerosis (MS) has been associated with both a poor vitamin D
status and hyperactivity of the hypothalamus–pituitary–adrenal (HPA) axis. Since nuclear receptor ligands may regulate each other, we explored the association of vitamin D3 supplements with circadian cortisol levels in a double-blind and placebo-controlled supplementation study.

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