Central theme in this lab is the understanding of ocular signal transduction as it relies on the optical parts of the eye and retina. Optical signal transduction is characterized by the retinal point-spread-function. The transparency of the relevant biological components is a critical factor. How transparency is achieved and how defects can be characterized are important research questions of this lab. Normal as well as pathological conditions, including surgical (LASIK, PRK) and transplantation effects are investigated. We have specialized in straylight at the retina (Introduction to retinal straylight). The work has led to an instrument for practical clinical assessment of straylight (glare sensitivity) called C-Quant, manufactured and marketed by the German firm Oculus.