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Netherlands Institute for Neuroscience

Our brain is our most complex and fascinating organ. Our brain is responsible for everything we do, think and experience. What mechanisms lie hidden within those one hundred billion nerve cells, linked by one hundred thousand kilometers of connections? The scientists of the Netherlands Institute for Neuroscience are working to answer these questions.


Van Someren Group

Hilde M Wesselius, Eva S van den Ende, Jelmer Alsma, Jan C Ter Maaten, Stephanie C E Schuit, Patricia M Stassen, Oscar J de Vries, Karin H A H Kaasjager, Harm R Haak, Frederiek F van Doormaal, Jacobien J Hoogerwerf, Caroline B Terwee, Peter M van de Ven, Frank H Bosch, Eus J W van Someren, Prabath W B Nanayakkara, “Onderzoeks Consortium Acute Geneeskunde” Acute Medicine Research Consortium Quality and Quantity of Sleep and Factors Associated With Sleep Disturbance in Hospitalized Patients JAMA Internal Medicine (2018)

Swaab Group

T.C. Thannickal, J. John, L. Shan, D.F. Swaab, M.F. Wu, L. Ramanathan, R. McGregor, K.T. Chew, M. Cornford, A. Yamanaka, A. Inutsuka, Rolf Fronczek, G.J. Lammers, P.F. Worley, J.M. Siegel Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy. Science Translational Medicine 10 (2018) Download

Kalsbeek Group

Jakob Wefers, Dirk van Moorsel, Jan Hansen, Niels J Connell, Bas Havekes, Joris Hoeks, Wouter D van Marken Lichtenbelt, Hélène Duez, Esther Phielix, A. Kalsbeek, Mark V Boekschoten, Guido J Hooiveld, Matthijs K C Hesselink, Sander Kersten, Bart Staels, Frank A J L Scheer, Patrick Schrauwen Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle Proceedings of the National Academy of Sciences of the United States of America (2018) Download

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