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Publications

Huitinga Group

Nina L Fransen, Cheng-Chih Hsiao, Marlijn van der Poel, Hendrik J Engelenburg, Kim Verdaasdonk, Maria C J Vincenten, Ester B M Remmerswaal, Tanja Kuhlmann, Matthew R J Mason, Jörg Hamann, Joost Smolders, Inge Huitinga Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions Brain 143 (2020) 1714-1730 Download

Huitinga Group

Nina Fransen, Jakob B A Crusius, Joost Smolders, Mark R Mizee, Corbert G van Eden, Sabina Luchetti, Ester B M Remmerswaal, Jörg Hamann, Matthew R J Mason, Inge Huitinga Post-mortem multiple sclerosis lesion pathology is influenced by single nucleotide polymorphisms Brain Pathology 30 (2020) 106-119 Download

Huitinga Group

H Geut, D H Hepp, E Foncke, H W Berendse, J M Rozemuller, I Huitinga, W D J van de Berg Neuropathological correlates of parkinsonian disorders in a large Dutch autopsy series Acta neuropathologica communications 8 (2020) 39 Download

Huitinga Group

Marlijn van der Poel, Willianne Hoepel, Jörg Hamann, Inge Huitinga, Jeroen den Dunnen IgG Immune Complexes Break Immune Tolerance of Human Microglia Journal of Immunology 205 (2020) 2511-2518 Download

Huitinga Group

Anatoly Korotkov, Noora Puhakka, Shalini Das Gupta, Niina Vuokila, Diede W M Broekaart, Jasper J Anink, Mette Heiskanen, Jenni Karttunen, Jackelien van Scheppingen, Inge Huitinga, James D Mills, Erwin A van Vliet, Asla Pitkänen, Eleonora Aronica Increased expression of miR142 and miR155 in glial and immune cells after traumatic brain injury may contribute to neuroinflammation via astrocyte activation Brain Pathology 30 (2020) 897-912 Download

Huitinga Group

Katharina Heß, Laura Starost, Nicholas W Kieran, Christian Thomas, Maria C J Vincenten, Jack Antel, Gianvito Martino, Inge Huitinga, Luke Healy, Tanja Kuhlmann Lesion stage-dependent causes for impaired remyelination in MS Acta Neuropathologica 140 (2020) 359-375 Download

Huitinga Group

Nina Schultz, Elin Byman, , I. Huitinga, Malin Wennström Levels of Retinal Amyloid-β Correlate with Levels of Retinal IAPP and Hippocampal Amyloid-β in Neuropathologically Evaluated Individuals Journal of Alzheimer's Disease 73 (2020) 1201-1209 Download

Huitinga Group

Joost Smolders, Nina L Fransen, Chen-Chih Hsiao, Jörg Hamann, Inge Huitinga Perivascular tissue resident memory T cells as therapeutic target in multiple sclerosis Expert Review of Neurotherapeutics 20 (2020) 835-848 Download

Huitinga Group, Swaab Group

Lin Zhang, Ronald W H Verwer, Paul J Lucassen, Inge Huitinga, Dick F Swaab Prefrontal cortex alterations in glia gene expression in schizophrenia with and without suicide Journal of Psychiatric Research 121 (2020) 31-38 Download

Huitinga Group

Chotima Böttcher, Marlijn van der Poel, Camila Fernández-Zapata, Stephan Schlickeiser, Julia K H Leman, Cheng-Chih Hsiao, Mark R Mizee, Adelia, Maria C J Vincenten, Desiree Kunkel, Inge Huitinga, Jörg Hamann, Josef Priller Single-cell mass cytometry reveals complex myeloid cell composition in active lesions of progressive multiple sclerosis Acta neuropathologica communications 8 (2020) 136 Download

Salta Group, Huitinga Group

Wei-Ting Chen, Ashley Lu, Katleen Craessaerts, Benjamin Pavie, Carlo Sala Frigerio, Nikky Corthout, Xiaoyan Qian, Jana Laláková, Malte Kühnemund, Iryna Voytyuk, Leen Wolfs, Renzo Mancuso, Evgenia Salta, Sriram Balusu, An Snellinx, Sebastian Munck, Aleksandra Jurek, Jose Fernandez Navarro, Takaomi C Saido, Inge Huitinga, Joakim Lundeberg, Mark Fiers, Bart De Strooper Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease Cell 182 (2020) 976-991 Download

La Fleur Group, Kalsbeek Group, Swaab Group, Huitinga Group

Martin Jt Kalsbeek, Samantha Ec Wolff, Nikita L Korpel, Susanne E la Fleur, Johannes A Romijn, Eric Fliers, Andries Kalsbeek, Dick F Swaab, Inge Huitinga, Elly M Hol, Chun-Xia Yi The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia JCI insight 5 (2020) Download

Huitinga Group

Cheng-Chih Hsiao, Nina L Fransen, Aletta M R van den Bosch, Kim I M Brandwijk, Inge Huitinga, Jörg Hamann, Joost Smolders White matter lesions in multiple sclerosis are enriched for CD20dim CD8+ tissue-resident memory T cells European Journal of Immunology (2020) Download

Verhaagen Group, Huitinga Group

Jeroen Melief, Marie Orre, Koen Bossers, Corbert G van Eden, Karianne G Schuurman, Matthew R J Mason, Joost Verhaagen, Jörg Hamann, Inge Huitinga Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis Acta neuropathologica communications 7 (2019) Download

Huitinga Group

Marlijn van der Poel, T. Ulas, Mark R Mizee, C.C. Hsiao, Suzanne S M Miedema, Adelia, Karianne Schuurman, B. Helder, S.W. Tas, J.L. Schultze, Jörg Hamann, I. Huitinga Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and multiple sclerosis-associated changes. Nature Communications 10 (2019) Download

Huitinga Group

Elin Byman, Nina Schultz, , I. Huitinga, Anna M Blom, Malin Wennström A Potential Role for α-Amylase in Amyloid-β-Induced Astrocytic Glycogenolysis and Activation Journal of Alzheimer's Disease 68 (2019) 205-217 Download

Huitinga Group

Melanie Laarman, G. Geeven, P. Barnett, , I. Huitinga, Gabriel J E Rinkel, Wouter de Laat, Ynte M Ruigrok, Jeroen Bakkers Chromatin conformation links putative enhancers in intracranial aneurysm-associated regions to potential candidate genes. Journal of the American Heart Association 8 (2019) Download

Huitinga Group

Jeroen G J van Rooij, Lieke H H Meeter, Shami Melhem, Diana A T Nijholt, Tsz Hang Wong, , I. Huitinga, Annemieke Rozemuller, Andre G Uitterlinden, Joyce G van Meurs, John C van Swieten Hippocampal transcriptome profiling combined with protein-protein interaction analysis elucidates Alzheimer's disease pathways and genes Neurobiology of Aging 74 (2019) 225-233 Download

Huitinga Group

Inge Huitinga, Mignon de Goeij, Natasja Klioueva Legal and Ethical Issues in Brain Banking Neuroscience Bulletin 35 (2019) 267-269 Download

Huitinga Group

J Smolders, Kirstin M Heutinck, N.L. Fransen, E.B.M. Remmerswaal, Pleun Hombrink, Ineke J M Ten Berge, R.A.W. Van Lier, Inge Huitinga, Jörg Hamann Tissue-resident memory T cells populate the human brain. Nature Communications 9 (2018) Download

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