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Publications

Huitinga Group

Iliana Michailidou, Janske G P Willems, Evert-Jan Kooi, Corbert van Eden, Stefan M Gold, Jeroen J G Geurts, Frank Baas, I. Huitinga, Valeria Ramaglia Complement C1q-C3-associated synaptic changes in multiple sclerosis hippocampus Annals of Neurology 77 (2015) 1007-26 Download

Huitinga Group

Karlijn J Doorn, John J P Brevé, Benjamin Drukarch, Hendrikus W Boddeke, I. Huitinga, Paul J Lucassen, Anne-Marie van Dam Brain region-specific gene expression profiles in freshly isolated rat microglia Frontiers in Cellular Neuroscience 9 (2015) 84 Download

Huitinga Group

Hema Mohan, Anita Friese, Stefanie Albrecht, Markus Krumbholz, Christina L Elliott, Ariel Arthur, Ramesh Menon, Cinthia Farina, Andreas Junker, Christine Stadelmann, Susan C Barnett, I. Huitinga, Hartmut Wekerle, Reinhard Hohlfeld, Hans Lassmann, Tanja Kuhlmann, Chris Linington, Edgar Meinl Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination Acta neuropathologica communications 2 (2014) 178 Download

Huitinga Group

Jochem M D Galama, Jan G Zoll, Kjerstin H Lanke, Arjan S de Jong, Jeroen Melief, Inge Huitinga, Marcel M Verbeek, Frank J M van Kuppeveld Saffold cardiovirus and multiple sclerosis Annals of Clinical and Translational Neurology 1 (2014) 618-21 Download

Huitinga Group

Lucia V Schottlaender, Henry Houlden, , I. Huitinga Mutant COQ2 in multiple-system atrophy The New England Journal of Medicine 371 (2014) 81 Download

Huitinga Group

Marie Orre, W. Kamphuis, Lana M Osborn, Jeroen Melief, Lieneke Kooijman, I. Huitinga, Jan Klooster, K. Bossers, Elly M Hol Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice Neurobiology of Aging 35 (2014) 1-14 Download

Huitinga Group

Debbie A E Hendrickx, Karianne G Schuurman, Michael van Draanen, Jörg Hamann, I. Huitinga Enhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia Journal of Neuroinflammation 11 (2014) 64 Download

Huitinga Group

J Smolders, E.B.M. Remmerswaal, K.G. Schuurman, J. Melief, C.G. Van Eden, R.A.W. Van Lier, I. Huitinga, J. Hamann Accumulation of differentiated CD8+ and CD4+ T cells in the human brain. Acta Neuropathologica 126 (2013) 525-535 Download

Huitinga Group

N. Samarasekera, R.A. Salman, I. Huitinga, N.M. Klioueva, C.A. McLean, H. Kretzschmar, C. Smith, J.W. Ironside Brain banking for neurological disorders. Lancet Neurology 12 (2013) 1096-1105 Download

Huitinga Group

J Smolders, K.G. Schuurman, M.E. van Strien, J. Melief, D.A. Hendrickx, E.M. Hol, C.G. Van Eden, S. Luchetti, I. Huitinga Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue. Journal of Neuropathology and Experimental Neurology 72 (2013) 91-105 Download

Swaab Group, Huitinga Group

J. Melief, S. De Wit, C.G. Van Eden, C. Teunissen, J. Hamann, B.M.J. Uitdehaag, D.F. Swaab, I. Huitinga HPA-Axis activity in multiple sclerosis correlates with disease severity, lesion type and gene expression in normal-appearing white matter. Acta Neuropathologica 126 (2013) 237-249 Download

Huitinga Group

J. Melief, K.G. Schuurman, M.D. Van de Garde, J Smolders, M. Van Eijk, J. Hamann, I. Huitinga Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed. GLIA 61 (2013) 1848-1861 Download

Huitinga Group

H.M. Nielsen, D. Ek, U. Avdic, C. Orbjorn, O. Hansson, I. Huitinga, R. Veerhuis, A.J.M. Rozemuller, A. Brun, L. Minthon, M. Wennstrom NG2 cells, a new trail for Alzheimer's disease mechanisms? Acta neuropathologica communications 1 (2013) 7 Download

Huitinga Group

D.A. Hendrickx, N. Koning, K.G. Schuurman, M.E. van Strien, C.G. Van Eden, J. Hamann, I. Huitinga Selective upregulation of scavenger receptors in and around demyelinating areas in multiple sclerosis. Journal of Neuropathology and Experimental Neurology 72 (2013) 106-118 Download

Huitinga Group

V. Ramaglia, T.R. Hughes, R.M. Donev, M.M. Ruseva, X. Wu, I. Huitinga, F. Baas, J.W. Neal, B.P. Morgan C3-dependent mechanism of microglial priming relevant to multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America 109 (2012) 965-970 Download

Huitinga Group

J. Melief, N. Koning, K.G. Schuurman, M.D. Van de Garde, J Smolders, R.M. Hoek, M. Van Eijk, J. Hamann, I. Huitinga Phenotyping primary human microglia: Tight regulation of LPS responsiveness. GLIA 60 (2012) 1506-1517 Download

Huitinga Group

M.D. Klok, S.R. Alt, A.J.M. Irurzun Lafitte, J.D. Turner, E.A.J.F. Lakke, I. Huitinga, C.P. Muller, F.G. Zitman, E.R. De Kloet, R.H. De Rijk Decreased expression of mineralocorticoid receptor mRNA and its splice variants in postmortem brain regions of patients with depressive disorder. Journal of Psychiatric Research 45 (2011) 871-878 Download

Huitinga Group, Swaab Group

S. Luchetti, I. Huitinga, D.F. Swaab Neurosteroid and GABA-A receptor alterations in Alzheimer's disease. Neuroscience 191 (2011) 6-21 Download

Huitinga Group

J. Smolders, S.M. Moen, J. Damoiseaux, I. Huitinga, T. Holmoy Vitamin D in the healthy and inflamed central nervous sytem. Journal of the Neurological Sciences 311 (2011) 37-43 Download

Huitinga Group

P.F. Durrenberger, S. Fernando, S.N. Kashefi, I. Ferrer, J.J. Hauw, D. Seilhean, C. Smith, R. Walker, S. Al-Sarraj, C. Troakes, M. Palkovits, M. Kasztner, I. Huitinga, T. Arzberger, D.T. Dexter, H. Kretzschmar, R. Reynolds Effects of antemortem and postmortem variables on human brain mRNA quality: a BrainNet Europe study. Journal of Neuropathology and Experimental Neurology 69 (2010) 70-81 Download

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